Probably not, not unless your lesson plans are very brief notes. If so, you could use the "Daily Things to Do" section. (The bottom 1/3 of each week is marked off in hour time blocks for appointments, the middle 1/3 for to-dos that are specific to that day, and the top 1/3 which would be good for GtD lists.) That middle section could serve as a space for lesson plans for a secondary teacher who teaches the same one or two subjects all day long.
If you are wanting to combine a lesson plan book, calendar, to-dos, etc. into one book, a better bet would be to start with a lesson plan book. One two-page spread would be your lessons. Flip the page, and the next two-page spread would be appointments, lists, documentation, etc.