no, I'm not worried about it. But that’s because I have a backup strategy I feel good about. If someone doesn’t have that in place, they SHOULD be worried.
First, I make a weekly bootable clone backup to an external hard drive, so I have an exact replica of my hard drive that is no more than a week old at any point.
Second, I use a service called BackBlaze that uploads my files via the internet to offsite storage. I have it selected to backup all my documents, settings, pictures, music, photos, and this includes my passwords. This data is encrypted so there is little chance of anyone being able to view any of my data.
Third, I synchronize 1Password with the iPhone version so I have the data there, too.
So with all that, I'm pretty comfortable with my setup. Now, and this isn’t intended to be a Mac vs PC rant, but most people using PCs are under secured and their personal data is at risk. At a MINIMUM, you should be running a strong anti virus app and a software firewall with outbound monitoring, i.e. if ANYTHING on your system tries to make an outbound connection that you haven’t previously approved, you are notified and asked to approve the connection request. But I would also strongly recommend PC users also run real time anti trojan software. All it takes is one nasty keylogger for you to compromise all your personal/confidential information, and that equals a really, really bad day.